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The scientist using AI to hunt for antibiotics just about everywhere

When he was just a teenager trying to decide what to do with his life, César de la Fuente compiled a list of the world’s biggest problems. He ranked them inversely by how much money governments were spending to solve them. Antimicrobial resistance topped the list.  Twenty years on, the problem...

The Download: AI-enhanced cybercrime, and secure AI assistants

The Download: AI-enhanced cybercrime, and secure AI assistants

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. AI is already making online crimes easier. It could get much worse. Just as software engineers are using artificial intelligence to help write code...

AI is already making online swindles easier. It could get much worse.

AI is already making online swindles easier. It could get much worse.

Anton Cherepanov is always on the lookout for something interesting. And in late August last year, he spotted just that. It was a file uploaded to VirusTotal, a site cybersecurity researchers like him use to analyze submissions for potential viruses and other types of malicious software, often...

What’s next for Chinese open-source AI

The past year has marked a turning point for Chinese AI. Since DeepSeek released its R1 reasoning model in January 2025, Chinese companies have repeatedly delivered AI models that match the performance of leading Western models at a fraction of the cost.  Just last week the Chinese firm...

Inside the marketplace powering bespoke AI deepfakes of real women

Civitai—an online marketplace for buying and selling AI-generated content, backed by the venture capital firm Andreessen Horowitz—is letting users buy custom instruction files for generating celebrity deepfakes. Some of these files were specifically designed to make pornographic images banned by...

The Download: A bid to treat blindness, and bridging the internet divide

The Download: A bid to treat blindness, and bridging the internet divide

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. The first human test of a rejuvenation method will begin “shortly” Life Biosciences, a small Boston startup founded by Harvard professor and...

The Download: why LLMs are like aliens, and the future of head transplants

The Download: why LLMs are like aliens, and the future of head transplants

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Meet the new biologists treating LLMs like aliens   How large is a large language model? We now coexist with machines so vast and so...

America’s coming war over AI regulation

America’s coming war over AI regulation

MIT Technology Review’s What’s Next series looks across industries, trends, and technologies to give you a first look at the future. You can read the rest of them here. In the final weeks of 2025, the battle over regulating artificial intelligence in the US reached a boiling point. On December 11,...

Yann LeCun’s new venture is a contrarian bet against large language models  

Yann LeCun is a Turing Award recipient and a top AI researcher, but he has long been a contrarian figure in the tech world. He believes that the industry’s current obsession with large language models is wrong-headed and will ultimately fail to solve many pressing problems.  Instead, he thinks...

The Download: next-gen nuclear, and the data center backlash

The Download: next-gen nuclear, and the data center backlash

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How next-generation nuclear reactors break out of the 20th-century blueprint   The popularity of commercial nuclear reactors has surged in...

Data centers are amazing. Everyone hates them.

Behold, the hyperscale data center!  Massive structures, with thousands of specialized computer chips running in parallel to perform the complex calculations required by advanced AI models. A single facility can cover millions of square feet, built with millions of pounds of steel, aluminum,...

The Download: introducing this year’s 10 Breakthrough Technologies

The Download: introducing this year’s 10 Breakthrough Technologies

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Introducing this year’s 10 Breakthrough Technologies  It’s easy to be cynical about technology these days. Many of the “disruptions” of the...