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Mechanistic interpretability: 10 Breakthrough Technologies 2026

Mechanistic interpretability: 10 Breakthrough Technologies 2026

Hundreds of millions of people now use chatbots every day. And yet the large language models that drive them are so complicated that nobody really understands what they are, how they work, or exactly what they can and can’t do—not even the people who build them. Weird, right? It’s also a problem....

Hyperscale AI data centers: 10 Breakthrough Technologies 2026

Hyperscale AI data centers: 10 Breakthrough Technologies 2026

In sprawling stretches of farmland and industrial parks, supersized buildings packed with racks of computers are springing up to fuel the AI race. These engineering marvels are a new species of infrastructure: supercomputers designed to train and run large language models at mind-­bending scale,...

Meet the new biologists treating LLMs like aliens

Meet the new biologists treating LLMs like aliens

How large is a large language model? Think about it this way. In the center of San Francisco there’s a hill called Twin Peaks from which you can view nearly the entire city. Picture all of it—every block and intersection, every neighborhood and park, as far as you can see—covered in sheets of...

The Download: the case for AI slop, and helping CRISPR fulfill its promise

The Download: the case for AI slop, and helping CRISPR fulfill its promise

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How I learned to stop worrying and love AI slop —Caiwei Chen If I were to locate the moment AI slop broke through into popular consciousness, I’d...

A new CRISPR startup is betting regulators will ease up on gene-editing

Here at MIT Technology Review we’ve been writing about the gene-editing technology CRISPR since 2013, calling it the biggest biotech breakthrough of the century. Yet so far, there’s been only one gene-editing drug approved. It’s been used commercially on only about 40 patients, all with sickle-cell...