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Reformulated antibodies could be injected for easier treatment

Reformulated antibodies could be injected for easier treatment

Antibody treatments for cancer and other diseases are typically delivered intravenously, requiring patients to go to a hospital and potentially spend hours receiving infusions. Now Professor Patrick Doyle and his colleagues have taken a major step toward reformulating antibodies so that they can be...

A I-designed proteins may help spot cancer

A I-designed proteins may help spot cancer

Researchers at MIT and Microsoft have used artificial intelligence to create molecular sensors that could detect early signs of cancer via a urine test. The researchers developed an AI model to design short proteins that are targeted by enzymes called proteases, which are overactive in cancer...

A new way to rejuvenate the immune system

As people age, their immune function weakens. Owing to shrinkage of the thymus, where T cells normally mature and diversify, populations of these immune cells become smaller and can’t react to pathogens as quickly. But researchers at MIT and the Broad Institute have now found a way to overcome that...

Measles cases are rising. Other vaccine-preventable infections could be next.

Measles cases are rising. Other vaccine-preventable infections could be next.

There’s a measles outbreak happening close to where I live. Since the start of this year, 34 cases have been confirmed in Enfield, a northern borough of London. Most of those affected are children under the age of 11. One in five have needed hospital treatment. It’s another worrying development for...

The scientist using AI to hunt for antibiotics just about everywhere

When he was just a teenager trying to decide what to do with his life, César de la Fuente compiled a list of the world’s biggest problems. He ranked them inversely by how much money governments were spending to solve them. Antimicrobial resistance topped the list.  Twenty years on, the problem...

ALS stole this musician’s voice. AI let him sing again.

ALS stole this musician’s voice. AI let him sing again.

There are tears in the audience as Patrick Darling’s song begins to play. It’s a heartfelt song written for his great-grandfather, whom he never got the chance to meet. But this performance is emotional for another reason: It’s Darling’s first time on stage with his bandmates since he lost the...

US deputy health secretary: Vaccine guidelines are still subject to change

US deputy health secretary: Vaccine guidelines are still subject to change

Over the past year, Jim O’Neill has become one of the most powerful people in public health. As the US deputy health secretary, he holds two roles at the top of the country’s federal health and science agencies. He oversees a department with a budget of over a trillion dollars. And he signed the...

An experimental surgery is helping cancer survivors give birth

An experimental surgery is helping cancer survivors give birth

This week I want to tell you about an experimental surgical procedure that’s helping people have babies. Specifically, it’s helping people who have had treatment for bowel or rectal cancer. Radiation and chemo can have pretty damaging side effects that mess up the uterus and ovaries. Surgeons are...

The first human test of a rejuvenation method will begin “shortly” 

When Elon Musk was at Davos last week, an interviewer asked him if he thought aging could be reversed. Musk said he hasn’t put much time into the problem but suspects it is “very solvable” and that when scientists discover why we age, it’s going to be something “obvious.” Not long after, the...

OpenAI’s latest product lets you vibe code science

OpenAI’s latest product lets you vibe code science

OpenAI just revealed what its new in-house team, OpenAI for Science, has been up to. The firm has released a free LLM-powered tool for scientists called Prism, which embeds ChatGPT in a text editor for writing scientific papers. The idea is to put ChatGPT front and center inside software that...