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Reformulated antibodies could be injected for easier treatment

Reformulated antibodies could be injected for easier treatment

Antibody treatments for cancer and other diseases are typically delivered intravenously, requiring patients to go to a hospital and potentially spend hours receiving infusions. Now Professor Patrick Doyle and his colleagues have taken a major step toward reformulating antibodies so that they can be...

A I-designed proteins may help spot cancer

A I-designed proteins may help spot cancer

Researchers at MIT and Microsoft have used artificial intelligence to create molecular sensors that could detect early signs of cancer via a urine test. The researchers developed an AI model to design short proteins that are targeted by enzymes called proteases, which are overactive in cancer...

A new way to rejuvenate the immune system

As people age, their immune function weakens. Owing to shrinkage of the thymus, where T cells normally mature and diversify, populations of these immune cells become smaller and can’t react to pathogens as quickly. But researchers at MIT and the Broad Institute have now found a way to overcome that...

A retinal reboot for amblyopia

A retinal reboot for amblyopia

In the vision disorder amblyopia (or “lazy eye”), impaired vision in one eye early in life causes neural connections in the brain’s visual system to shift toward supporting the other eye, leaving the amblyopic eye less capable even if the original impairment is corrected. Current interventions...

Just pull a string to turn these tile patterns into useful 3D structures

Just pull a string to turn these tile patterns into useful 3D structures

MIT researchers have developed a new method for designing 3D structures that can spring up from a flat sheet of interconnected tiles with a single pull of a string. The technique could be used to make foldable bike helmets and medical devices, emergency shelters and field hospitals for disaster...

The Download: radioactive rhinos, and the rise and rise of peptides

The Download: radioactive rhinos, and the rise and rise of peptides

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Why conservationists are making rhinos radioactive Every year, poachers shoot hundreds of rhinos, fishing crews haul millions of sharks out of...

Why conservationists are making rhinos radioactive

Why conservationists are making rhinos radioactive

Every year, poachers shoot hundreds of rhinos, fishing crews haul millions of sharks out of protected seas, and smugglers carry countless animals and plants across borders. This illegal activity is incredibly hard to disrupt, since it’s backed by sophisticated criminal networks and the perpetrators...

The Download: Chicago’s surveillance network, and building better bras

The Download: Chicago’s surveillance network, and building better bras

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Inside Chicago’s surveillance panopticon Chicago has tens of thousands of surveillance cameras—up to 45,000, by some estimates.  That’s among the...

Inside Chicago’s surveillance panopticon

Inside Chicago’s surveillance panopticon

Early on the morning of September 2, 2024, a Chicago Transit Authority Blue Line train was the scene of a random and horrific mass shooting. Four people were shot and killed on a westbound train as it approached the suburb of Forest Park.  The police swiftly activated a digital dragnet—a...