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Why some “breakthrough” technologies don’t work out

Why some “breakthrough” technologies don’t work out

Every year, MIT Technology Review publishes a list of 10 Breakthrough Technologies. In fact, the 2026 version is out today. This marks the 25th year the newsroom has compiled this annual list, which means its journalists and editors have now identified 250 technologies as breakthroughs.  A few...

How next-generation nuclear reactors break out of the 20th-century blueprint

How next-generation nuclear reactors break out of the 20th-century blueprint

Commercial nuclear reactors all work pretty much the same way. Atoms of a radioactive material split, emitting neutrons. Those bump into other atoms, splitting them and causing them to emit more neutrons, which bump into other atoms, continuing the chain reaction.  That reaction gives off...

Meet the new biologists treating LLMs like aliens

Meet the new biologists treating LLMs like aliens

How large is a large language model? Think about it this way. In the center of San Francisco there’s a hill called Twin Peaks from which you can view nearly the entire city. Picture all of it—every block and intersection, every neighborhood and park, as far as you can see—covered in sheets of...

Good technology should change the world

Good technology should change the world

The billionaire investor Peter Thiel (or maybe his ghostwriter) once said, “We were promised flying cars, instead we got 140 characters.” That quip originally appeared in a manifesto for Thiel’s venture fund in 2011. All good investment firms have a manifesto, right? This one argued for making bold...

The Download: the case for AI slop, and helping CRISPR fulfill its promise

The Download: the case for AI slop, and helping CRISPR fulfill its promise

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. How I learned to stop worrying and love AI slop —Caiwei Chen If I were to locate the moment AI slop broke through into popular consciousness, I’d...

America’s new dietary guidelines ignore decades of scientific research

America’s new dietary guidelines ignore decades of scientific research

The new year has barely begun, but the first days of 2026 have brought big news for health. On Monday, the US’s federal health agency upended its recommendations for routine childhood vaccinations—a move that health associations worry puts children at unnecessary risk of preventable disease. There...

Using unstructured data to fuel enterprise AI success

Using unstructured data to fuel enterprise AI success

Enterprises are sitting on vast quantities of unstructured data, from call records and video footage to customer complaint histories and supply chain signals. Yet this invaluable business intelligence, estimated to make up as much as 90% of the data generated by organizations, historically remained...

Deploying a hybrid approach to Web3 in the AI era

Deploying a hybrid approach to Web3 in the AI era

When the concept of “Web 3.0” first emerged about a decade ago the idea was clear: Create a more user-controlled internet that lets you do everything you can now, except without servers or intermediaries to manage the flow of information. Where Web2, which emerged in the early 2000s, relies on...

The Download: war in Europe, and the company that wants to cool the planet

The Download: war in Europe, and the company that wants to cool the planet

This is today’s edition of The Download, our weekday newsletter that provides a daily dose of what’s going on in the world of technology. Europe’s drone-filled vision for the future of war Last spring, 3,000 British soldiers deployed an invisible automated intelligence network, known as...

The man who made India digital isn’t done yet

The man who made India digital isn’t done yet

Nandan Nilekani can’t stop trying to push India into the future. He started nearly 30 years ago, masterminding an ongoing experiment in technological state capacity that started with Aadhaar—the world’s largest digital identity system. Aadhaar means “foundation” in Hindi, and on that bedrock...